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/Sounds like "pee" (as in "pea") + "KAHR" (as in "car") + "seh" (as in "set")/

Meaning

To get offended, take something personally, or feel called out by something said in general. In Mexico, if someone 'se pica,' they reacted to a comment that wasn't even directed at them, which usually means it hit closer to home than they'd like to admit.

Examples

Why are you getting offended? Nobody was even talking about you specifically.

He took the joke personally and left angry without saying goodbye to anyone.

Word family
Regional synonyms

To be inseparable friends, that duo that always goes everywhere together like a perfect combination. It's the Latino way of saying two people work so well together they just don't function as well apart.